Due to using the DamStandard brush and making a crease between the chest and underarm, I now want to fill it in, but I’m finding it difficult to remove the crease. I’ve tried splitting both sides apart with the Move brush and building the area up with the ClayBuildup, but it isn’t working. I’ve tried using ZModeler to bridge the gap, but haven’t been successful. Any ideas what I could do here?
Thanks
Please upgrade to the most recent version of Zbrush, which is currently zb2012.1.2. This is free for registered users, and obsolete versions are not officially supported. Continued use of an outdated version is going to impair our ability to assist you.
The standard Clay brush might be able to “spackle” that recess. However most users would probably just smooth this out and correct it as desired.
If you have multiple subdivision levels, it may be easier to smooth on a lower level of subdivision–one of the perks of sculpting fine detail with a traditional multi-SubD process. Otherwise, if it proves resistant to smoothing, you may have to adjust the intensity or other modifiers of the active smooth brush, or select an alternate smooth brush that provides better results.
Okay, I’ve cleaned it up mostly thanks to using the Clay brush and smoothing it, but now I’ve discovered a hole in my geometry around the armpit. Dynamesh fixes this, but then I lose all of my detail, even if I try to Project the detail back onto it. :-\
Screenshots should really be a first resort for issues like these. An experienced user can often spot an issue on sight that a new user may not have developed the vocabulary to adequately communicate yet. No one will ever waste a post chiding you for providing too much information about your problem. 
As far as I can tell from your description, there are two things going on here.
1-The “hole”.
First, make sure it actually is a hole, and not a display issue with a twisted normal which would be somewhat more common. In Tool> Display Properties, switch on “Double”. If the hole disappears, it’s just an issue with a polygon being twisted around. Further smoothing should fix it.
If it is actually a gap in the polygons, further smoothing will likely enlarge the hole. If you have no subdivision levels, you can fix it short of a full Dynamesh by using Tool> Geometry > Modify Topology > Close Hole.
If you do have subD levels, you will have to Freeze Subdivision levels to fix it at the base level either with Dynamesh or Close Holes.
2-Loss of detail during Dynamesh.
You have to increase the resolution slider to capture increasingly finer amounts of detail with Dynamesh.
If you are using “Freeze Subdivision levels” on a mesh with multiple subdivision levels the detail from your original will not be projected until you exit Freeze Subdivision Levels mode. This mode is essentially an automated version of the subtool projection method described here.
Mesh scale matters with Dynamesh. If your mesh is abnormally small in the Zbrush worldspace, you may have trouble capturing all the detail even with max Resolution.
If increasing the resolution slider fails to capture the detail, or takes a prohibitively long time to complete, you are working outside of the optimal range for Dynamesh. You should transition to a multiple subD level sculpting process for sculpting fine detail. I believe I’ve already explained to you how to do this, but will provide that info again upon request.
Thanks for the suggestions. In the end, I managed to sort it. To begin with, projecting my copied details from a duplicate was also copying the hole across as well, even after getting rid of it using Dynamesh, Inflate, smooth, and ZRemesh. So I tried masking the area out that had the hole so that detail didn’t get transferred across. 
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Thank you.
