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Cursor offcenter of brush ciricle - Help Please

Can anyone tell me what might be causing this issue? My cursor (plus symbol or pointer) is off-center on the brush circle. It only happens in r8 and 2018 it started about a week ago, I have no idea what might have caused it. I am on a mac. The red dot shows where the cursor is positioned. For some reason, screenshots do not show the cursor so had to draw the dot.

I am hoping this is simply a matter of me fat-fingering something but it is quite annoying as the cursor is several pixels away from the center which means when you go to click a button 9 times out of 10 it clicks the wrong button or nothing at all. Also the smaller the brush the MORE off-center, the larger the brush the more its closer to the center but the brush is so large you simply would never have it that big to work with. I have reinstalled ZBrush, Wacom drivers, mouse drivers same issue. The cursor is in that position whether I am using the mouse or the pen, and even after dozens of calibrations. Lastly, it is only off in ZBrush. Any help would be so greatly appreciated.

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Hopefully this will help: https://support.pixologic.com/Knowledgebase/Article/View/206/0/mac-os-cursors-position-is-off-target